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CASE REPORT article

Front. Oncol.
Sec. Neuro-Oncology and Neurosurgical Oncology
Volume 14 - 2024 | doi: 10.3389/fonc.2024.1493982

Spontaneous rupture of a giant mature teratoma in the lateral ventricle: a case report

Provisionally accepted
Yong Xiao Yong Xiao Liang Liu Liang Liu *Ran Wang Ran Wang Dong Wang Dong Wang *Chong Xiang Chong Xiang *Pan Li Pan Li Yiqin Wu Yiqin Wu *Liangyuan Geng Liangyuan Geng Xinhua Hu Xinhua Hu Yong Liu Yong Liu *Chunfa Qian Chunfa Qian Hongyi Liu Hongyi Liu Yuanjie Zou Yuanjie Zou *
  • Nanjing Medical University, Nanjing, China

The final, formatted version of the article will be published soon.

    We present the case of an adolescent female patient diagnosed with a ruptured lateral ventricle teratoma. Distinctive radiological and microscopic findings revealed floating oily globules within the ventricles and subarachnoid space. The spontaneous rupture of the teratoma may be attributed to age-dependent hormonal changes, which increase glandular secretion, cyst content volume, and intra-cystic pressure. The patient underwent gross total resection of the tumor, and subsequent pathological examination proved mature teratoma. Postoperatively, she was managed with routine follow-up without adjuvant chemotherapy or radiotherapy. During the 1-year follow-up period, the patient remained asymptomatic with no evidence of tumor recurrence. Based on this case, we recommend that gross total resection, followed by close monitoring without adjunctive chemotherapy or radiotherapy, can be an effective treatment strategy for patients with similar presentations.

    Keywords: giant teratoma, Rupture, the lateral ventricle, Adolescent Female, case report

    Received: 10 Sep 2024; Accepted: 23 Dec 2024.

    Copyright: © 2024 Xiao, Liu, Wang, Wang, Xiang, Li, Wu, Geng, Hu, Liu, Qian, Liu and Zou. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence:
    Liang Liu, Nanjing Medical University, Nanjing, China
    Dong Wang, Nanjing Medical University, Nanjing, China
    Chong Xiang, Nanjing Medical University, Nanjing, China
    Yiqin Wu, Nanjing Medical University, Nanjing, China
    Yong Liu, Nanjing Medical University, Nanjing, China
    Yuanjie Zou, Nanjing Medical University, Nanjing, China

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