Skip to main content

MINI REVIEW article

Front. Oncol.
Sec. Gastrointestinal Cancers: Hepato Pancreatic Biliary Cancers
Volume 14 - 2024 | doi: 10.3389/fonc.2024.1483306
This article is part of the Research Topic Molecular Markers for Pancreatic Cancers: New Technologies and Applications in the Clinical Practice View all 7 articles

Emerging horizons on molecular and circulating biomarkers in Pancreatic adenocarcinoma

Provisionally accepted
Marta Moretti Marta Moretti Antonella Farina Antonella Farina Antonio Angeloni Antonio Angeloni Emanuela Anastasi Emanuela Anastasi *
  • Sapienza University of Rome, Rome, Lazio, Italy

The final, formatted version of the article will be published soon.

    Pancreatic ductal adenocarcinoma (PDAC) is the most aggressive and invasive type of pancreatic cancer and is expected to soon become the second leading cause of cancerassociated death. The high mortality rate is due to the clinical features that allow asymptomatic progression to advanced stages, a period when current therapeutic treatments have limited efficacy. To address these challenges, researchers are focused on identifying new molecular and circulating markers for early PDAC detection and precision medicine. In this mini-review, we report the most well-known and recently identified molecular and circulating biomarkers. This study aimed to emphasize the need for continued innovative research to develop diagnostic algorithms and therapies to improve the management of patients with PDAC.

    Keywords: Pancreas, Adenocarcinoma, markers, diagnosis, target therapy

    Received: 19 Aug 2024; Accepted: 17 Oct 2024.

    Copyright: © 2024 Moretti, Farina, Angeloni and Anastasi. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence: Emanuela Anastasi, Sapienza University of Rome, Rome, 00185, Lazio, Italy

    Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.