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CASE REPORT article

Front. Oncol.
Sec. Gynecological Oncology
Volume 14 - 2024 | doi: 10.3389/fonc.2024.1482768
This article is part of the Research Topic Management of Rare Oncological Cases View all 43 articles

Mullerian adenosarcoma accidentally detected and coexisting with cervical carcinoma in situ: a rare case report

Provisionally accepted
Xuemei Qing Xuemei Qing 1,2*Min Xie Min Xie 1,3Hongying Guo Hongying Guo 1Liying Zhang Liying Zhang 1Jiatian Ye Jiatian Ye 3Yong Zhang Yong Zhang 2,4Ying Ma Ying Ma 4,5
  • 1 People's Hospital of Qingbaijiang District, Chengdu, China
  • 2 Southwest Medical University, Luzhou, Sichuan, China
  • 3 West China Second University Hospital, Sichuan University, Chengdu, Sichuan Province, China
  • 4 Mianyang Central Hospital, Mianyang, Sichuan Province, China
  • 5 Chengdu Medical College, Chengdu, Sichuan, China

The final, formatted version of the article will be published soon.

    Mullerian adenosarcoma is rare, usually in the uterine corpus and rarely in the cervix.Adenosarcoma which grows diffusely in the uterine cavity and the cervical canal is even rarer without symptoms. Herein, we report a rare case of multiple primary malignant neoplasms of Mullerian adenosarcoma accidentally detected and coexisting with cervical carcinoma in situ. Fortunately, the tumor was in the early stage and the Mullerian adenosarcoma was treated together with the cervical carcinoma in situ by a surgical procedure of hysterectomy + bilateral adnexectomy. Histopathology and immunohistochemistry results confirmed this diagnosis, further confirmed by a pathology consultation at the University Hospital. She recovered well from the surgical treatment and was discharged with regular follow-up. This patient didn't undergo the pelvis-abdomen CT and diagnostic curettage preoperatively, and no malignancy was detected by cryo-pathology intraoperatively, which may be related to the rarity of the disease and the relative lack of awareness and experience of our clinicians and pathologists for this tumor. We hope this rare case can provide some lessons for gynecologists and pathologists.

    Keywords: Mullerian adenosarcoma, Cervical carcinoma in situ, Multiple primary malignant neoplasms, rare, case report

    Received: 18 Aug 2024; Accepted: 19 Sep 2024.

    Copyright: © 2024 Qing, Xie, Guo, Zhang, Ye, Zhang and Ma. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence: Xuemei Qing, People's Hospital of Qingbaijiang District, Chengdu, China

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