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CASE REPORT article

Front. Oncol.
Sec. Skin Cancer
Volume 14 - 2024 | doi: 10.3389/fonc.2024.1478747

Basal cell carcinoma arising within the nevus sebaceous: report of 4 cases and literature review

Provisionally accepted
Tianbing Lei Tianbing Lei Yonghong Lu Yonghong Lu Yanyan Feng Yanyan Feng Yao Ni Yao Ni *
  • Department of Dermatovenereology, Chengdu Second People's Hospital, Chengdu, China

The final, formatted version of the article will be published soon.

    Nevus sebaceous (NS) is a congenital hamartoma characterized by the presence of skin structures, including the epidermis, sebaceous glands, and hair follicles. NS predominantly occurs on the scalp and has the potential to give rise to secondary tumors, with a small proportion being malignant; the most frequently observed malignant tumor associated with NS is basal cell carcinoma. In this report, we retrospectively present four cases of sebaceous nevus on the scalp complicated by basal cell carcinoma. The pathological diagnoses were unequivocal in all four patients, who exhibited typical clinical manifestations, with all cases localized to the left parietotemporal region of the scalp. The etiology of NS may be linked to genetic mutations or ultraviolet exposure. Treatment options vary, with surgical resection likely being the most common method of eradication.

    Keywords: Nevus sebaceous, basal cell carcinoma, Malignant degeneration, gene, Ultraviolet

    Received: 10 Aug 2024; Accepted: 13 Dec 2024.

    Copyright: © 2024 Lei, Lu, Feng and Ni. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence: Yao Ni, Department of Dermatovenereology, Chengdu Second People's Hospital, Chengdu, China

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