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CASE REPORT article

Front. Oncol.
Sec. Hematologic Malignancies
Volume 14 - 2024 | doi: 10.3389/fonc.2024.1471654

Preoperative Diagnosis of Primary Ovarian Lymphoma: a case report and a decade of insights

Provisionally accepted
Wei Liu Wei Liu 1*Houyun Xu Houyun Xu 1Jibo Hu Jibo Hu 1Xiping Yu Xiping Yu 2Junjie Zhou Junjie Zhou 1Hongjie Hu Hongjie Hu 3,4
  • 1 Department of Radiology, the Fourth Affiliated Hospital of School of Medicine, and International School of Medicine, International Institutes of Medicine, Zhejiang University, Yiwu, China, 322000;, Yiwu, China
  • 2 Department of Pathology, the Fourth Affiliated Hospital of School of Medicine, and International School of Medicine, International Institutes of Medicine, Zhejiang University, Yiwu, China, 322000;, Yiwu, China
  • 3 Department of Radiology, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China;, Hangzhou, China
  • 4 Medical imaging international scientific and technological cooperation base of Zhejiang province, Zhejiang, China

The final, formatted version of the article will be published soon.

    Through a comprehensive retrospective analysis of a 52 -year -old woman with POL and a review of similar cases in the PubMed database over the past decade, we have gained several key insights to improve the understanding of POL among clinicians and radiologists for accurate diagnosis. POLs are more prevalent among women in their forties. POLs usually present with clinical manifestations a solid mass (typically over 10 cm) and abdominal pain with B symptoms. Four imaging features show promise as indicators of potential diagnostic value in POL, such as ovarian retention sign, touching ovaries, vascular floatation, and the sandwich sign. More than half of primary ovarian DLBCL cases have elevated LDH or CA125 levels. This comprehensive understanding of POL suggests that integrate these four imaging features with elevated level of CA125 and LDH may help to diagnose POL preoperatively, preventing unnecessary surgical interventions.

    Keywords: Primary ovarian lymphoma1, imaging features2, diffuse large B cell lymphoma3, hematologic malignant4, Diagnosis5

    Received: 28 Jul 2024; Accepted: 18 Nov 2024.

    Copyright: © 2024 Liu, Xu, Hu, Yu, Zhou and Hu. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence: Wei Liu, Department of Radiology, the Fourth Affiliated Hospital of School of Medicine, and International School of Medicine, International Institutes of Medicine, Zhejiang University, Yiwu, China, 322000;, Yiwu, China

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