Skip to main content

CASE REPORT article

Front. Oncol.
Sec. Hematologic Malignancies
Volume 14 - 2024 | doi: 10.3389/fonc.2024.1467237

Hemangiopericytoma following allogeneic hematopoietic stem cell transplantation in a patient with primary plasma cell leukemia: the first case report

Provisionally accepted
Yajun Shi Yajun Shi Guohao Liang Guohao Liang Haiying Zhang Haiying Zhang Yaqing Wang Yaqing Wang Ying Han Ying Han Shenglian Tong Shenglian Tong Shunyu Liang Shunyu Liang Ying Wang Ying Wang Hai Bai Hai Bai Rui Xi Rui Xi *
  • People's Liberation Army Joint Logistics Support Force 940th Hospital, Lanzhou, China

The final, formatted version of the article will be published soon.

    Background: Hemangiopericytoma (HPC) is a rare secondary tumor after allogeneic hematopoietic stem cell transplantation (allo-HSCT), which has not been reported in the literature. Herein, we reported a case of HPC after allo-HSCT.We report a case of a middle-aged female patient with primary plasma cell leukemia who presented lumbosacral pain and right lower limb pain and numbness on1684 days post-transplant. She underwent an MRI of the lumbar spine, which showed abnormal signal intensity in the spinal canal at the second through fifth lumbar spine vertebral levels. The patient was diagnosed with HPC based on a pathological biopsy of the diseased tissue in the spinal canal. Radiotherapy was administered to the lesion in the second through fifth lumbar vertebrae. The patient experienced less numbness and pain.According to the literature, this is the first reported case of post-transplant HPC. Therefore, attention should be paid to secondary tumors after transplantation, especially rare tumors.

    Keywords: Primary plasma cell leukemia, Allogeneic hematopoietic cell transplantation, Secondary tumors, Hemangiopericytoma, case report

    Received: 19 Jul 2024; Accepted: 21 Oct 2024.

    Copyright: © 2024 Shi, Liang, Zhang, Wang, Han, Tong, Liang, Wang, Bai and Xi. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence: Rui Xi, People's Liberation Army Joint Logistics Support Force 940th Hospital, Lanzhou, China

    Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.