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CASE REPORT article

Front. Oncol.
Sec. Cancer Imaging and Image-directed Interventions
Volume 14 - 2024 | doi: 10.3389/fonc.2024.1463362

A rare case of malignant solitary fibrous tumor within the joint cavity with review of the literature

Provisionally accepted
Xiao-Jie Wang Xiao-Jie Wang 1Jia-Ping Zhou Jia-Ping Zhou 1Yao Pan Yao Pan 1Risheng Yu Risheng Yu 1,2*
  • 1 Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang Province, China
  • 2 School of Medicine, Graduate School, Zhejiang University, Hangzhou, China

The final, formatted version of the article will be published soon.

    Solitary fibrous tumor (SFT) is classified as fibroblastic/myofibroblastic tumors which originate from CD34-positive dendritic cell and usually occurs in pleura. We here describe a case of SFT within the joint cavity of left knee. A 60-year-old man was admitted to hospital because his left knee had swollen for the past eight months without relevant trauma history. X-ray, computed tomography (CT), magnetic resonance imaging (MRI) and positron emission tomography-computed tomography (PET-CT) presented a large, ill-circumscribed, hyper-vascular and highly enhancing mass with eccentric calcification and peripheral, intra-lesional vessels. Then the patient underwent surgical resection. Postoperative pathology confirmed the neoplastic cells were positive for CD34, Bcl-2 and SATA6, so it was finally diagnosed as malignant SFT. The patient developed bone metastases within one year after surgery. SFT in the joint cavity is rare and is hard to make a preoperative diagnosis.

    Keywords: Solitary fibrous tumor, Joint, computed tomography, Magnetic Resonance Imaging, Positron emission tomography-computed tomography

    Received: 11 Jul 2024; Accepted: 11 Nov 2024.

    Copyright: © 2024 Wang, Zhou, Pan and Yu. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence: Risheng Yu, School of Medicine, Graduate School, Zhejiang University, Hangzhou, China

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