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REVIEW article
Front. Oncol.
Sec. Cancer Immunity and Immunotherapy
Volume 14 - 2024 |
doi: 10.3389/fonc.2024.1461324
This article is part of the Research Topic Exploring Oncolytic Virotherapy in Solid Tumor Treatment View all 6 articles
Innovative Strategies in Genitourinary Cancer: The Role of Oncolytic Viruses
Provisionally accepted
Jie Zhang
1,2
Kepu Liu
2*
Shihao Shang
2
Wei Di
2
Yu Zheng
2
Lei Zhang
2*
Ying Liang
3
Dongen Ju
2*
Jianlin Yuan
2*- 1 College of Life Sciences, Northwest University, Xi'an, China
- 2 Xijing Hospital, Fourth Military Medical University, Xi'an, China
- 3 Precision Pharmacy & Drug Development Center, Department of Pharmacy, Tangdu Hospital, Air Force Medical University, Xi'an, Shaanxi Province, China
Urinary tumors pose a significant health threat because of their high prevalence and recurrence rates. Despite the availability of various treatment options, many patients poorly respond to traditional therapies, highlighting the urgent need for alternative approaches. Oncolytic viruses are promising therapeutic agents. These viruses exploit the unique characteristics of cancer cells to specifically target and destroy them, thereby triggering potent antitumor immune responses. This review delves into recent advancements and future prospects of oncolytic viruses, focusing on their application in renal, bladder, and prostate cancers. By discussing practical implications and the potential of different viruses, including the cowpox virus, adenovirus, measles virus, coxsackievirus, and reovirus, we pave the way for further exploration and refinement of this exciting field.
Keywords: oncolytic virus, renal cancer, Bladder cancer, prostate cancer, tumor, therapy
Received: 08 Jul 2024; Accepted: 09 Sep 2024.
Copyright: © 2024 Zhang, Liu, Shang, Di, Zheng, Zhang, Liang, Ju and Yuan. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence:
Kepu Liu, Xijing Hospital, Fourth Military Medical University, Xi'an, China
Lei Zhang, Xijing Hospital, Fourth Military Medical University, Xi'an, China
Dongen Ju, Xijing Hospital, Fourth Military Medical University, Xi'an, China
Jianlin Yuan, Xijing Hospital, Fourth Military Medical University, Xi'an, China
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