Skip to main content

CASE REPORT article

Front. Oncol.
Sec. Gynecological Oncology
Volume 14 - 2024 | doi: 10.3389/fonc.2024.1461216
This article is part of the Research Topic Management of Rare Oncological Cases View all 55 articles

Case Report:A Successful Live Birth after In Vitro Fertilization and Embryo Transfer in a Patient with Endometrial Cancer Who Was Treated Conservatively

Provisionally accepted
Yifan Fan Yifan Fan 1,2,3Hui Song Hui Song 2,3,4Pei Zhang Pei Zhang 4Jingwen Si Jingwen Si 2Hui Dong Hui Dong 2,3,4Xu Chen Xu Chen 2,3,4*
  • 1 Nankai University, Tianjin, China
  • 2 Tianjin Central Hospital for Gynecology and Obstetrics, Tianjin, China
  • 3 Tianjin Key Laboratory of Human Development and Reproductive Regulation, Tianjin, China
  • 4 School of Medicine, Nankai University, Tianjin, China

The final, formatted version of the article will be published soon.

    Objective: To describe a patient conceiving with in vitro fertilization and embryo transfer(IVF-ET) after conservative treatment of early stage endometrial cancer. Design: Case report. Setting: Tianjin Central Hospital of Gynecology Obstetrics, Tianjin, China. Patient: A 31-year-old multiparous woman diagnosed with highly-differentiated (G1)endometrial adenocarcinoma (grade IA). Intervention(s): After four courses of conservative treatment each followed by hysteroscopic biopsy and endometrial curettage,assisted reproductive technology was performed. Main Outcome Measure(s): Successful pregnancy and delivery without residual endometrial cancer. Results(s): A healthy normal female infant with a birth weight of 3,690 g was born by cesarean section at 38+2 weeks’ gestation. No residual malignant cells was detected on a biopsy during cesarean section. Conclusion(s): Conservative fertility-sparing treatment are crucial for young patients with early stage endometrial cancer. Assisted reproductive technologies may be considered to assist such patients to conceive as soon as possible.

    Keywords: Early-stage endometrial cancer, fertility-sparing treatment, conservative treatment, in vitro fertilization and embryo transfer, Pregnancy

    Received: 08 Jul 2024; Accepted: 25 Nov 2024.

    Copyright: © 2024 Fan, Song, Zhang, Si, Dong and Chen. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence: Xu Chen, School of Medicine, Nankai University, Tianjin, 300192, China

    Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.