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CASE REPORT article

Front. Oncol.
Sec. Skin Cancer
Volume 14 - 2024 | doi: 10.3389/fonc.2024.1449270
This article is part of the Research Topic Management of Rare Oncological Cases View all 48 articles

Metastatic Endocrine Mucin-Producing Sweat Gland Carcinoma with Features of Mucinous Carcinoma

Provisionally accepted
Yuehua Sun Yuehua Sun Yingchun Liu Yingchun Liu *Chuntao Li Chuntao Li *Xiaodong Zhang Xiaodong Zhang *Lu Yin Lu Yin *Jun Niu Jun Niu *
  • General Hospital of Northern Theater Command, Shenyang, China

The final, formatted version of the article will be published soon.

    Endocrine mucin-producing sweat gland carcinoma is a rare neoplasm of the skin appendages.The tumor typically exhibits slow growth and rarely metastasizes to distant sites. Herein, we report a case of a 77-year-old male who presented with a skin lesion on the right anterior chest wall 23 years ago. Fifteen years later, surgical excision was performed, and the pathological diagnosis was endocrine mucin-producing sweat gland carcinomas. However, the histopathological examination revealed a coexistence of endocrine mucin-producing sweat gland carcinomas and mucinous carcinoma components. Over the past 2 years, the patient developed lymph node metastasis in the right axilla, local recurrence on the right chest wall, and distant skin metastasis. The histopathological type of the lymph node metastasis was consistent with the primary tumor, while the recurrent and skin metastatic lesions exhibited mucinous carcinoma. To our knowledge, this is the first reported case of endocrine mucin-producing sweat gland carcinoma with distant skin metastasis, characterized by two distinct carcinoma components in the histopathological morphology.

    Keywords: Endocrine mucin-producing sweat gland carcinoma, Mucinous carcinoma, neoplasm, metastases, Immunohistochemistry

    Received: 14 Jun 2024; Accepted: 18 Oct 2024.

    Copyright: © 2024 Sun, Liu, Li, Zhang, Yin and Niu. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence:
    Yingchun Liu, General Hospital of Northern Theater Command, Shenyang, China
    Chuntao Li, General Hospital of Northern Theater Command, Shenyang, China
    Xiaodong Zhang, General Hospital of Northern Theater Command, Shenyang, China
    Lu Yin, General Hospital of Northern Theater Command, Shenyang, China
    Jun Niu, General Hospital of Northern Theater Command, Shenyang, China

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