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CASE REPORT article

Front. Oncol.
Sec. Surgical Oncology
Volume 14 - 2024 | doi: 10.3389/fonc.2024.1449171

Anesthesia management of CRS and HIPEC in advanced ovarian cancer with ultra-high intra-abdominal pressure: a case report

Provisionally accepted
  • 1 Department of Anesthesiology Aerospace Center Hospital, Beijing, China
  • 2 Department of Myxomatology, Aerospace Center Hospital, Beijing, China, Beijing, China

The final, formatted version of the article will be published soon.

    Cytoreductive surgery (CRS) combined with hyperthermic intraperitoneal chemotherapy (HIPEC) is a leading treatment for advanced ovarian cancer, significantly improving overall survival and disease-free survival. This case involves a patient with peritoneal metastasis and ultra-high intraabdominal pressure (36 mmHg). CRS + HIPEC induces extensive pathological and physiological changes affecting respiratory, circulatory, renal, coagulation, and metabolic systems. Effective perioperative anesthesia management, including the type and volume of fluids administered, is crucial for optimizing patient outcomes. The complexities of anesthesia management in such cases present significant challenges.

    Keywords: ovarian cancer, Cytoreductive surgery, Hyperthermic intraperitoneal chemotherapy, Intra-Abdominal Hypertension, Anesthetic management, Goal-directed fluid therapy, temperature

    Received: 14 Jun 2024; Accepted: 11 Nov 2024.

    Copyright: © 2024 Chen, LIN, Gao, Liu, Yang, Ma and Lu. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence:
    Ruiqing Ma, Department of Myxomatology, Aerospace Center Hospital, Beijing, China, Beijing, China
    Liangyuan Lu, Department of Anesthesiology Aerospace Center Hospital, Beijing, China

    Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.