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CASE REPORT article

Front. Oncol.
Sec. Genitourinary Oncology
Volume 14 - 2024 | doi: 10.3389/fonc.2024.1442293

Acute Pancreatitis and Biliary Obstruction from Metastatic Lymph Node Compression During [ 177 Lu] Lu-PSMA-617 Therapy: A Case Report

Provisionally accepted
Gokce Belge Bilgin Gokce Belge Bilgin *Patrick J. Navin Patrick J. Navin Derek R. Johnson Derek R. Johnson Oliver Sartor Oliver Sartor Ayse T. Kendi Ayse T. Kendi
  • Mayo Clinic, Rochester, United States

The final, formatted version of the article will be published soon.

    Radioligand therapies such as [ 177 Lu] Lu-PSMA-617 have gained significant momentum in cancer treatment after clinical trials and multicenter studies demonstrated their safety and efficacy. As these innovative treatments become more widespread, rare and unique clinical manifestations are expected to be observed. In this report, we describe a case with metastatic castration-resistant prostate cancer (mCRPC) and peripancreatic lymph node metastases who developed acute pancreatitis following [ 177 Lu] Lu-PSMA-617 therapy.

    Keywords: prostate cancer, Lu-PSMA, theranosctics, acute pancreatitis, Inflammation

    Received: 01 Jun 2024; Accepted: 16 Sep 2024.

    Copyright: © 2024 Belge Bilgin, Navin, Johnson, Sartor and Kendi. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence: Gokce Belge Bilgin, Mayo Clinic, Rochester, United States

    Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.