Skip to main content

CASE REPORT article

Front. Oncol.
Sec. Neuro-Oncology and Neurosurgical Oncology
Volume 14 - 2024 | doi: 10.3389/fonc.2024.1438011
This article is part of the Research Topic Clinical Therapy of Brain Tumors View all 16 articles

A rare case of neurocytoma of the Vth cranial nerve

Provisionally accepted
Shuhong Mei Shuhong Mei 1Fanghua Zhou Fanghua Zhou 1*Bin Li Bin Li 1*Bin Wu Bin Wu 1*Xingen Huang Xingen Huang 1*Zhaomu Zeng Zhaomu Zeng 2*Yongping Gui Yongping Gui 2*
  • 1 Ji'an Central People's Hospital, Ji'an, Jiangxi Province, China
  • 2 Jiangxi Provincial People's Hospital, Nanchang, China

The final, formatted version of the article will be published soon.

    We report a case of neurocytoma originating from cranial nerve V. A 53-year-old female patient presented with a 20-day history of right frontotemporal facial paresthesia and pain. Magnetic resonance imaging (MRI) showed a 2.5-cm × 1.4-cm “dumbbell” enhancing lesion located in the cisternal segment of cranial nerve V with extension into Meckel’s cave, and the signal characteristics were suggestive of trigeminal neurinoma. The lesion was resected through a subtemporal middle cranial fossa approach. Intraoperative findings revealed that the tumor originated from the cisternal segment of cranial nerve V and extended into Meckel’s cave through the trigeminal foramen. No dural attachment was found. The tumor was debulked using sharp dissection and bipolar cautery under the microscope. Extraventricular neurocytomas (EVNs) are extremely rare tumors of the central nervous system. To date, only two cases of neurocytomas arising from cranial nerve Ⅷ have been described. This paper summarizes the clinicopathological features of a case of neurocytoma originating from the cisternal segment of cranial nerve V with extension into Meckel’s cave and expounds the relevant diagnoses and treatments, which may provides a practical clinical basis and experience for the diagnosis and treatment of EVN in the future.

    Keywords: Extraventricular neurocytoma, Trigeminal Nerve, Immunohistochemistry, origin and pathological basis, case report

    Received: 24 May 2024; Accepted: 12 Sep 2024.

    Copyright: © 2024 Mei, Zhou, Li, Wu, Huang, Zeng and Gui. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence:
    Fanghua Zhou, Ji'an Central People's Hospital, Ji'an, 343000, Jiangxi Province, China
    Bin Li, Ji'an Central People's Hospital, Ji'an, 343000, Jiangxi Province, China
    Bin Wu, Ji'an Central People's Hospital, Ji'an, 343000, Jiangxi Province, China
    Xingen Huang, Ji'an Central People's Hospital, Ji'an, 343000, Jiangxi Province, China
    Zhaomu Zeng, Jiangxi Provincial People's Hospital, Nanchang, China
    Yongping Gui, Jiangxi Provincial People's Hospital, Nanchang, China

    Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.