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CASE REPORT article

Front. Oncol.
Sec. Thoracic Oncology
Volume 14 - 2024 | doi: 10.3389/fonc.2024.1437535

Case report: A case of giant malignant solitary fibrous tumor of the pleura with Doege-Potter's syndrome and review of the literature

Provisionally accepted
Jie Li Jie Li 1Hong-Tao Tang Hong-Tao Tang 2Qing Liu Qing Liu 1,3Li Caihan Li Caihan 4Wei-Yang Chen Wei-Yang Chen 5Zeng-Wei Yu Zeng-Wei Yu 1Lei Wang Lei Wang 1Lin Lin Lin Lin 1Jin-Lan Zhao Jin-Lan Zhao 6,7Chun-Yan Zhao Chun-Yan Zhao 8Long-Qi Chen Long-Qi Chen 1Dong Tian Dong Tian 9*
  • 1 Department of Thoracic Surgery, West China Hospital, Sichuan University, Chengdu, Sichuan Province, China
  • 2 Department of Cardiovascular Surgery, West China Hospital, Sichuan University, Chengdu, China
  • 3 Integrated Care management center, West China Hospital, Sichuan University, Chengdu, China
  • 4 Department of Radiology, West China Hospital, Sichuan University, Chengdu, Sichuan Province, China
  • 5 Department of Thoracic Surgery, The First Affiliated Hospital of China Medical University, Shenyang, Liaoning Province, China
  • 6 Anesthesia surgery center, West China hospital, Sichuan University, Chengdu, China
  • 7 West China School of Nursing, Sichuan University, Chengdu, China
  • 8 Department of Nuclear Medicine, West China Hospital, Sichuan University, Chengdu, Sichuan Province, China
  • 9 West China Hospital, Sichuan University, Chengdu, China

The final, formatted version of the article will be published soon.

    The solitary fibrous tumor of the pleura (SFTP) is a rare intrathoracic neoplasm that commonly originates from the subpleural mesenchymal cells of the visceral pleura and accounts for less than 5% of all pleural tumors. We reported a case of a 54-year-old man with a two-week history of hypoglycemia, a six-month history of productive cough and fatigue, and chronic right chest pain. Radiological techniques revealed a giant intra-thoracic mass with hypervascularization, and pathological staining was carried out to make a definitive diagnosis of SFTP. Interventional embolization was conducted to block the main feeding vessels before the surgery, and an anterolateral thoracotomy combined with a transverse sternotomy was performed to achieve a complete resection, which demonstrates significant potential for further application in patients with unilateral giant SFTP. The postoperative course was uneventful, with no signs of hypoglycemia observed during the follow-up. Additionally, we reviewed and prospected the research progress on SFTP. The aim of this study is to enhance clinicians' understanding of SFTP through our case and to provide a detailed review of the current research.

    Keywords: Solitary fibrous tumor of the pleura, Doege-Potter's syndrome, surgical resection, surgical approach, Malignant lesion, Hypoglycemia

    Received: 23 May 2024; Accepted: 08 Nov 2024.

    Copyright: © 2024 Li, Tang, Liu, Caihan, Chen, Yu, Wang, Lin, Zhao, Zhao, Chen and Tian. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence: Dong Tian, West China Hospital, Sichuan University, Chengdu, China

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