Juan Du
Shuang Ye
Hui Zhang
Zhen Zheng
Kaitai Liu
*The final, formatted version of the article will be published soon.
REVIEW article
Front. Oncol.
Sec. Cancer Molecular Targets and Therapeutics
Volume 14 - 2024 |
doi: 10.3389/fonc.2024.1436576
Unraveling IFI44L's biofunction in Human Disease
Provisionally accepted- Ningbo Medical Centre Lihuili Hospital, Ningbo, Zhejiang Province, China
Interferon-induced protein 44-like (IFI44L) is regarded as an immunerelated gene and is a member of interferon-stimulated genes (ISGs). They participate in network transduction, and its own epigenetic modifications, apoptosis, cell-matrix formation, and many other pathways in tumors, autoimmune diseases, and viral infections. The current review provides a comprehensive overview of the onset and biological mechanisms of IFI44L and its potential clinical applications in malignant tumors and nonneoplastic diseases.
Keywords: biomarker, diagnosis, immune response, Interferon-induced protein 44-like (IFI44L)，Therapeutic target, tumor
Received: 22 May 2024; Accepted: 26 Nov 2024.
Copyright: © 2024 Du, Luo, Ye, Zhang, Zheng and Liu. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence:
Kaitai Liu, Ningbo Medical Centre Lihuili Hospital, Ningbo, 315010, Zhejiang Province, China
Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.