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CASE REPORT article

Front. Oncol.
Sec. Surgical Oncology
Volume 14 - 2024 | doi: 10.3389/fonc.2024.1434542

A Rare Case Report of Hyaline-Vascular Type Castleman Disease in the Presacral Region

Provisionally accepted
Long Chang Long Chang Shuang Wang Shuang Wang *Min Wang Min Wang *Jiannan Li Jiannan Li Zeyun Zhao Zeyun Zhao
  • Second Affiliated Hospital of Jilin University, Changchun, China

The final, formatted version of the article will be published soon.

    Castleman disease (CD), also known as giant lymph node hyperplasia or angiofollicular lymph node hyperplasia, is a rare and indeterminate group of chronic lymphoproliferative disorders. CD is highly heterogeneous, classified into unicentric Castleman disease (UCD) and multicentric Castleman disease (MCD) based on lesion distribution, and further categorized into three pathological types: hyaline vascular type (HV), plasma cell type (PC), and mixed type (Mix). This paper describes a rare case of solitary mediastinal Castleman disease with transparent vessels in the anterior sacrum, presenting as the HV type. Surgical excision of the mass was performed following coccygectomy for treatment. The patient recovered well postoperatively. During a 6-month follow-up period, there were no signs of recurrence, and the patient's quality of life significantly improved.

    Keywords: Castleman disease hyaline-vascular variant, presacral mass, Unicentric Castleman disease (UCD), Surgery, MRI, CT, Pathological examination diagnosis

    Received: 25 May 2024; Accepted: 30 Jul 2024.

    Copyright: © 2024 Chang, Wang, Wang, Li and Zhao. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence:
    Shuang Wang, Second Affiliated Hospital of Jilin University, Changchun, China
    Min Wang, Second Affiliated Hospital of Jilin University, Changchun, China

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