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ORIGINAL RESEARCH article

Front. Oncol.
Sec. Thoracic Oncology
Volume 14 - 2024 | doi: 10.3389/fonc.2024.1434326

The value of multiple diffusion metrics based on whole-lesion histogram analysis in evaluating the subtypes and proliferation status of non-small cell lung cancer

Provisionally accepted
Yao Chen Yao Chen Hong Yang Hong Yang *Yuan Qin Yuan Qin *Chuanjiang Guan Chuanjiang Guan *Wenbing Zeng Wenbing Zeng *Yong Luo Yong Luo *
  • Chongqing Three Gorges Central Hospital, Chongqing, China

The final, formatted version of the article will be published soon.

    The manuscript investigates the utility of whole-lesion histogram analysis using intravoxel incoherent motion (IVIM) and diffusion kurtosis imaging (DKI) in discerning subtypes and proliferation status of non-small cell lung cancer (NSCLC). This study aligns with the scope of Frontiers in Thoracic Oncology by advancing understanding in imaging techniques for characterizing NSCLC, which is crucial for precise diagnosis, treatment planning, and prognostication in thoracic oncology. By exploring novel quantitative metrics and their correlations with histological markers, the research contributes valuable insights into the non-invasive assessment of NSCLC, thereby enhancing the management strategies and outcomes in thoracic oncology.

    Keywords: Yao Chen: Data curation, Funding acquisition, methodology, Writing -original draft, Writing -review & editing. Wenbing Zeng: Formal Analysis, project administration, resources, supervision

    Received: 17 May 2024; Accepted: 08 Oct 2024.

    Copyright: © 2024 Chen, Yang, Qin, Guan, Zeng and Luo. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence:
    Hong Yang, Chongqing Three Gorges Central Hospital, Chongqing, China
    Yuan Qin, Chongqing Three Gorges Central Hospital, Chongqing, China
    Chuanjiang Guan, Chongqing Three Gorges Central Hospital, Chongqing, China
    Wenbing Zeng, Chongqing Three Gorges Central Hospital, Chongqing, China
    Yong Luo, Chongqing Three Gorges Central Hospital, Chongqing, China

    Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.