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CASE REPORT article

Front. Oncol.
Sec. Surgical Oncology
Volume 14 - 2024 | doi: 10.3389/fonc.2024.1432274
This article is part of the Research Topic Extending the Limit of Liver Cancer Treatment with Surgical Options View all articles

Case Report: Outflow Reconstruction with Pre-Frozen Allograft Blood Vessels during In vivo Partial Hepatectomy followed by Ex vivo Tumor Resection and Partial Liver Autotransplantation for Locally Advanced Hepatocellular Carcinoma with Background of Cirrhosis

Provisionally accepted
Junze Chen Junze Chen Junze Chen Junze Chen *Cheng Zhang Cheng Zhang *Rui-Ling Su Rui-Ling Su *Yong-Yuan Jian Yong-Yuan Jian *Kai-Yong Huang Kai-Yong Huang *Xue-Lin Tan Xue-Lin Tan *Zhao Chen Zhao Chen *Yong-Xin Liao Yong-Xin Liao *Chunqiang Dong Chunqiang Dong Kun Dong Kun Dong *
  • First Affiliated Hospital, Guangxi Medical University, Nanning, China

The final, formatted version of the article will be published soon.

    Ex vivo surgery and autotransplantation may provide a promising chance for radical resection of conventionally unresectable liver tumors. Two cirrhotic patients with hepatocellular carcinoma (HCC), which has an "awkward seat" located in the "intrahepatic vascular triangle area (IVTA)" that consists of the middle hepatic vein (MHV), the right branches of glisson sheath, and the inferior vena cava (IVC), underwent in vivo extended right-half hepatectomy following by ex vivo tumor resection and partial liver autotransplantation. Innovatively, the outflow of the tumor-free liver was reconstructed ex vivo by using pre-frozen allograft blood vessels from brain death donors, they recovered well post operation. We report the surgical experience to provide a novel curable surgical procedure for locally advanced IVAT liver tumors.

    Keywords: autotransplantation, Hepatocellular Carcinoma, Hepatectomy, in vivo, ex vivo, Vascular allograft

    Received: 13 May 2024; Accepted: 25 Nov 2024.

    Copyright: © 2024 Chen, Chen, Zhang, Su, Jian, Huang, Tan, Chen, Liao, Dong and Dong. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence:
    Junze Chen, First Affiliated Hospital, Guangxi Medical University, Nanning, China
    Cheng Zhang, First Affiliated Hospital, Guangxi Medical University, Nanning, China
    Rui-Ling Su, First Affiliated Hospital, Guangxi Medical University, Nanning, China
    Yong-Yuan Jian, First Affiliated Hospital, Guangxi Medical University, Nanning, China
    Kai-Yong Huang, First Affiliated Hospital, Guangxi Medical University, Nanning, China
    Xue-Lin Tan, First Affiliated Hospital, Guangxi Medical University, Nanning, China
    Zhao Chen, First Affiliated Hospital, Guangxi Medical University, Nanning, China
    Yong-Xin Liao, First Affiliated Hospital, Guangxi Medical University, Nanning, China
    Kun Dong, First Affiliated Hospital, Guangxi Medical University, Nanning, China

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