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CASE REPORT article

Front. Oncol.
Sec. Thoracic Oncology
Volume 14 - 2024 | doi: 10.3389/fonc.2024.1431950

Primary endobronchial multifocal Ewing's sarcoma: a rare case report

Provisionally accepted
Dan Liu Dan Liu 1Xiaoge Liu Xiaoge Liu 2*Xin Li Xin Li 1*Yisha Liu Yisha Liu 1*Junlun Yu Junlun Yu 1*
  • 1 Sichuan Academy of Medical Sciences and Sichuan Provincial People's Hospital, Chengdu, China
  • 2 Ya'an People’s Hospital, Yaan, Sichuan Province, China

The final, formatted version of the article will be published soon.

    Extraskeletal Ewing's sarcoma (ES) has been reported to originate from various sites. Primary endobronchial ES is an extremely rare bronchial tumor, especially multifocal lesions.This report describes a rare presentation of primary bronchial ES in a 31-year-old female who was referred to the emergency department of our hospital due to suspicion of a foreign body in the bronchus. Computed tomography and bronchoscopy revealed multiple polypoid nodules in the middle bronchus of her right lung, thus excluding the initial diagnosis. Infection-related laboratory tests and serum tumor markers were normal. The bronchial sleeve resection was performed to remove the tumor completely and the patient's clinical symptoms obviously improved. Subsequent imaging, histopathological, immunohistochemical and genetic analyses made a conclusive diagnosis of primary endobronchial ES. To our knowledge, this is the eighth case of primary bronchial ES reported in medical literature.

    Keywords: Ewing's sarcoma, Endobronchus, Thoracic tumor, EWSR1-FLI1 fusion gene, case report

    Received: 13 May 2024; Accepted: 25 Jun 2024.

    Copyright: © 2024 Liu, Liu, Li, Liu and Yu. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence:
    Xiaoge Liu, Ya'an People’s Hospital, Yaan, 625000, Sichuan Province, China
    Xin Li, Sichuan Academy of Medical Sciences and Sichuan Provincial People's Hospital, Chengdu, China
    Yisha Liu, Sichuan Academy of Medical Sciences and Sichuan Provincial People's Hospital, Chengdu, China
    Junlun Yu, Sichuan Academy of Medical Sciences and Sichuan Provincial People's Hospital, Chengdu, China

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