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REVIEW article

Front. Oncol.
Sec. Breast Cancer
Volume 14 - 2024 | doi: 10.3389/fonc.2024.1429262
This article is part of the Research Topic Non-coding RNAs in Breast Cancer - Volume II View all 3 articles

The Emerging Roles of LINC00511 in Breast Cancer Development and Therapy

Provisionally accepted
Lifeng Zhao Lifeng Zhao 1,2Sangita Biswas Sangita Biswas 3*Yepeng Li Yepeng Li 1*Suren R. SOORANNA Suren R. SOORANNA 4
  • 1 Affiliated Hospital of Youjiang Medical University for Nationalities, Baise, Guangx, China
  • 2 Faculty of Medicine, Bioscience, and Nursing, Mahsa University, Selangor, Malaysia
  • 3 Department of Preclinical Sciences, Faculty of Medicine and Biomedical Sciences, Mahsa University, Selangor, Malaysia
  • 4 Department of Metabolism,Digestion and Reproduction, Faculty of Medicine, Imperial College London, London, United Kingdom

The final, formatted version of the article will be published soon.

    Breast cancer (BC) is associated with malignant tumors in women worldwide with persistently high incidence and mortality rates. The traditional therapies including surgery, chemotherapy, radiotherapy and targeted therapy have certain therapeutic effects on BC patients, but acquired drug resistance can lead to tumor recurrence and metastasis.This remains a clinical challenge that is difficult to solve during treatment.Therefore, continued research is needed to identify effective targets and treatment methods, to ultimately implement personalized treatment strategies. Several studies have implicated that the long non-coding RNA LINC00511 is closely linked to the occurrence, development and drug resistance of BC. Here we will review the structure and the mechanisms of action of lnc RNA LINC00511 in various cancers, and then explore its expression and its related regulatory mechanisms during BC. In addition, we will discuss the biological functions and the potential clinical applications of LINC00511 in BC.

    Keywords: lncRNAs, LINC00511, breast cancer, mechanisms, Biological function lncRNAs, Dev]:

    Received: 07 May 2024; Accepted: 29 Jul 2024.

    Copyright: © 2024 Zhao, Biswas, Li and SOORANNA. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence:
    Sangita Biswas, Department of Preclinical Sciences, Faculty of Medicine and Biomedical Sciences, Mahsa University, Selangor, Malaysia
    Yepeng Li, Affiliated Hospital of Youjiang Medical University for Nationalities, Baise, 533000, Guangx, China

    Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.