Skip to main content

SYSTEMATIC REVIEW article

Front. Oncol.
Sec. Cancer Epidemiology and Prevention
Volume 14 - 2024 | doi: 10.3389/fonc.2024.1424812
This article is part of the Research Topic The Future of Cancer Surveillance Research View all 24 articles

Application of Mendelian Randomized Research method in Oncology Research: Bibliometric Analysis

Provisionally accepted
Jiahao Chen Jiahao Chen Yunli Wang Yunli Wang Rongsheng Jiang Rongsheng Jiang Yawei Qu Yawei Qu *Yan Li Yan Li *Yang Zhang Yang Zhang *
  • Changchun University of Chinese Medicine, Changchun, Jilin Province, China

The final, formatted version of the article will be published soon.

    Background: Cancer has always been a difficult problem in the medical field, and with the gradual deepening of Genome-wide association studies (GWAS), Mendelian randomization methods have been increasingly used to study cancer pathogenesis. In this study, we examine the literature on Mendelian cancer, summarize the status of the research, and analyze the development trends in the field.Methods: Publications on "Mendelian Randomization -Cancer" were retrieved and downloaded from the Web of Science Core Collection database. CiteSpace 6.2.R4, VOSviewer 1.6.19, Scimago Graphica 1.0.38, Bibliometrix R-package, and a bibliometric online analysis platform were used for data analysis and visualization. An in-depth analysis of country or region, authors, journals, keywords, and references was performed to provide insights into the content related to the field.Results: A total of 836 articles were included in the analysis; 643 authors from 72 countries had published articles related to the field. China and Harvard University (among countries and institutions, respectively) had the highest number of articles. Martin, Richard M and Smith, George Davey were the largest contributors. A total of 27 cancers have been studied, with breast, colorectal, and liver cancers being the most studied.This study is the first to use bibliometric methods to visualize the application of Mendelian randomization analysis in the field of cancer, revealing research trends and research frontiers in the field. This information will provide a strong reference for cancer researchers and epidemiologic researchers.

    Keywords: Cancer, Mendelian randomization, bibliometric analysis, Epidemiology, cancer risk, tumors, Carcinoma, genome-wide association studies

    Received: 28 Apr 2024; Accepted: 26 Nov 2024.

    Copyright: © 2024 Chen, Wang, Jiang, Qu, Li and Zhang. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence:
    Yawei Qu, Changchun University of Chinese Medicine, Changchun, 130117, Jilin Province, China
    Yan Li, Changchun University of Chinese Medicine, Changchun, 130117, Jilin Province, China
    Yang Zhang, Changchun University of Chinese Medicine, Changchun, 130117, Jilin Province, China

    Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.