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REVIEW article
Front. Oncol.
Sec. Molecular and Cellular Oncology
Volume 14 - 2024 |
doi: 10.3389/fonc.2024.1419599
Integrating Frontiers: A Holistic, Quantum and Evolutionary Approach to Conquering Cancer through Systems Biology and Multidisciplinary Synergy
Provisionally accepted- 1 Federal University of Espirito Santo, Vitória, Brazil
- 2 Grupo de Bioanalítica, Microfabricação e Separações (BioMicS), São Carlos-SP, Brazil
- 3 Laboratório de Estudos Neuroquímicos, Universidade Federal do Rio Grande do Norte (UFRN), Rio Grande do Norte, Brazil., Brazil
- 4 Roberto Alcantara Gomes Institute of Biology, State University of Rio de Janeiro, Rio de Janeiro, Rio de Janeiro, Brazil
- 5 Department of Analytical Chemistry and Physical Chemistry, Science Center, Federal University of Ceara, Fortaleza, Ceará, Brazil
Cancer therapy is facing increasingly significant challenges, marked by a wide range of techniques and research efforts centered around somatic mutations, precision oncology, and the vast amount of big data. Despite this abundance of information, the quest to cure cancer often seems more elusive, with the "war on cancer" yet to deliver a definitive victory. A particularly pressing issue is the development of tumor treatment resistance, highlighting the urgent need for innovative approaches. Evolutionary, Quantum Biolgy and System Biology offer a promising framework for advancing experimental cancer research. By integrating theoretical studies, translational methods, and flexible multidisciplinary clinical research, there's potential to enhance current treatment strategies and improve outcomes for cancer patients. Establishing stronger links between evolutionary, quantum, entropy and chaos principles and oncology could lead to more effective treatments that leverage an understanding of the tumor's evolutionary dynamics, paving the way for novel methods to control and mitigate cancer. Achieving these objectives necessitates a commitment to multidisciplinary and interprofessional collaboration at the heart of both research and clinical endeavors in oncology. This entails dismantling silos between disciplines, encouraging open communication and data sharing, and integrating diverse viewpoints and expertise from the outset of research projects. Being receptive to new scientific discoveries and responsive to how patients react to treatments is also crucial. Such strategies are key to keeping the field of oncology at the forefront of effective cancer management, ensuring patients receive the most personalized and effective care. Ultimately, this approach aims to push the boundaries of cancer understanding, treating it as a manageable chronic condition, aiming to extend life expectancy and enhance patient quality of life.
Keywords: Neoplasms, Carcinogenesis, Biological Evolution, Chaos and Quantum Theory, dynamics, translational science
Received: 30 Apr 2024; Accepted: 31 Jul 2024.
Copyright: © 2024 Casotti, Meira, Zetum, Campanharo, da Silva, Giacinti, da Silva, Moura, Barbosa, Altoé, Mauricio, Góes, Alves, Linhares, Ventorim, Guaitolini, dos Santos, Errera, Groisman, CARVALHO, de Paula, Fechine and Louro. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence:
Matheus C. Casotti, Federal University of Espirito Santo, Vitória, Brazil
Débora D. Meira, Federal University of Espirito Santo, Vitória, Brazil
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