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CASE REPORT article
Front. Oncol.
Sec. Hematologic Malignancies
Volume 14 - 2024 |
doi: 10.3389/fonc.2024.1419485
Platelet HLA gene bank digital matching technology for platelet transfusion refractory patients with malignant tumors: a case report
Provisionally accepted- 1 Haining People's Hospital, Jiaxing, China
- 2 Other, Jiaxing, China
The platelet human leucocyte antigen(HLA) gene bank contains the genetic information of HLA loci in a large number of blood donors.Currently, the most effective treatment for platelet transfusion refractory (PTR) is to evaluate the probability of antigenic mismatch by HLA genotyping of patients, and to select HLA-matched donors in the gene bank through an information system. This case report describes the treatment of PTR in patients with malignant tumors using platelet HLA gene bank digital matching technique. The analysis of individual cases will help guide transfusion strategies for such patients.
Keywords: HLA, Platelet, PTR, Gene bank, Malignant tumor
Received: 18 Apr 2024; Accepted: 02 Sep 2024.
Copyright: © 2024 Gao, LI, Ni, Wang, Hu and Zhu. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence:
jianhua LI, Other, Jiaxing, China
Xiuwen Ni, Other, Jiaxing, China
Lijun Wang, Haining People's Hospital, Jiaxing, China
Peilin Hu, Haining People's Hospital, Jiaxing, China
Xiaowei Zhu, Haining People's Hospital, Jiaxing, China
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