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CASE REPORT article

Front. Oncol.
Sec. Hematologic Malignancies
Volume 14 - 2024 | doi: 10.3389/fonc.2024.1419485

Platelet HLA gene bank digital matching technology for platelet transfusion refractory patients with malignant tumors: a case report

Provisionally accepted
Xiang Gao Xiang Gao 1jianhua LI jianhua LI 2*Xiuwen Ni Xiuwen Ni 2*Lijun Wang Lijun Wang 1*Peilin Hu Peilin Hu 1*Xiaowei Zhu Xiaowei Zhu 1*
  • 1 Haining People's Hospital, Jiaxing, China
  • 2 Other, Jiaxing, China

The final, formatted version of the article will be published soon.

    The platelet human leucocyte antigen(HLA) gene bank contains the genetic information of HLA loci in a large number of blood donors.Currently, the most effective treatment for platelet transfusion refractory (PTR) is to evaluate the probability of antigenic mismatch by HLA genotyping of patients, and to select HLA-matched donors in the gene bank through an information system. This case report describes the treatment of PTR in patients with malignant tumors using platelet HLA gene bank digital matching technique. The analysis of individual cases will help guide transfusion strategies for such patients.

    Keywords: HLA, Platelet, PTR, Gene bank, Malignant tumor

    Received: 18 Apr 2024; Accepted: 02 Sep 2024.

    Copyright: © 2024 Gao, LI, Ni, Wang, Hu and Zhu. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence:
    jianhua LI, Other, Jiaxing, China
    Xiuwen Ni, Other, Jiaxing, China
    Lijun Wang, Haining People's Hospital, Jiaxing, China
    Peilin Hu, Haining People's Hospital, Jiaxing, China
    Xiaowei Zhu, Haining People's Hospital, Jiaxing, China

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