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SYSTEMATIC REVIEW article

Front. Oncol.
Sec. Breast Cancer
Volume 14 - 2024 | doi: 10.3389/fonc.2024.1419123
This article is part of the Research Topic Reviews in Breast Cancer: 2023 View all 27 articles

Comparison of endoscopic breast-conserving surgery versus conventional breast-conserving surgery for the treatment of early-stage breast cancer: a meta-analysis

Provisionally accepted
LiWen Li LiWen Li Yiwen Liang Yiwen Liang Chunyan Li Chunyan Li Miaoyan Huang Miaoyan Huang Weiming Liang Weiming Liang *Tian Qin Tian Qin *
  • Guangxi University of Science and Technology, Liuzhou, China

The final, formatted version of the article will be published soon.

    This meta-analysis seeks to evaluate the efficacy and safety of endoscopic breast-conserving surgery(E-BCS) compared to conventional breast cancer surgery(C-BCS) in patients diagnosed with early-stage breast cancer. Materials and methods: Four databases(Medline, Embase, Web of Science and CENTRAL) were searched published from establishment of database to January 30,2024, for articles studying E-BCS compared to C-BCS in patients diagnosed with early-stage breast cancer.Meta-analyses of procedure time, blood loss, length of incision, drainage duration, total postoperative drainage volume, average duration of hospital stay, positive rate of margin, complication rate, recurrence rate, metastasis rate and cosmetic scoring were performed. Results: Totally 11 studies were included for meta-analysis. Compared with C-BCS, E-BCS exhibited significantly reduced incision length(WMD = -6.44, 95%CI: -10.78 to -2.11, P=0.004, I 2 =99.0%) and superior cosmetic scoring(WMD = 2.69, 95%CI: 1.46 to 3.93, P=0.001, I 2 =93.2%), but had significantly longer operation time(WMD = 34.22, 95%CI: 20.89~47.55, P=0.000, I 2 =90.7%) and blood loss(WMD = 3.65, 95%CI: -3.12 to 10.43, P=0.291, I 2 =86.8%). There was no significant difference in † Liwen Li and Yiwen Liang are co-first authors. * Weiming Liang and Tian Qin are co-corresponding authors terms of recurrence rate, metastasis rate, positive rate of tumor resection margins, drainage duration, drainage volume, complication rate and hospital days. Conclusions: Our research findings indicate that E-BCS is a viable and secure method for treating breast cancer in its early stages. E-BCS provides distinct advantages in terms of the length of the incision and the aesthetic result, without demonstrating an elevated recurrence rate or metastasis rate.Trial registration PROSPERO(CRD42023446653)

    Keywords: breast cancer, Breast-conserving surgery, endoscopic, Recurrence, Meta-analysis

    Received: 17 Apr 2024; Accepted: 23 Jul 2024.

    Copyright: © 2024 Li, Liang, Li, Huang, Liang and Qin. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence:
    Weiming Liang, Guangxi University of Science and Technology, Liuzhou, China
    Tian Qin, Guangxi University of Science and Technology, Liuzhou, China

    Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.