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ORIGINAL RESEARCH article

Front. Oncol.
Sec. Gastrointestinal Cancers: Gastric and Esophageal Cancers
Volume 14 - 2024 | doi: 10.3389/fonc.2024.1409411

Risk Factors for Early Readmission to Hospital in Patients with Malignancy-related Ascites: A retrospective cohort study

Provisionally accepted
Qingbo Guan Qingbo Guan *Zhenhua Tian Zhenhua Tian Zhilong Huang Zhilong Huang Yaqi Guo Yaqi Guo Xiaolin Zhao Xiaolin Zhao Luna Liu Luna Liu Chunxiao Yu Chunxiao Yu
  • Shandong Provincial Hospital, Jinan, China

The final, formatted version of the article will be published soon.

    Malignancy-related ascites (MRA) is a common serious complication of many advanced malignant tumors with high morbidity and mortality. The high hospital expenditures induced by unplanned readmission in patients with MRA have become an urgent issue to the public. We aimed to overall assess the unplanned early readmission rate of patients with MRA and explore the potential risk factors for such readmission. A retrospective cohort study based on 2018 Nationwide Readmissions Database was performed and patients with MRA were recruited into the analysis. The primary outcome was unplanned 30-day readmission rate and inpatient outcomes. The multivariate logistic regression analysis was performed to evaluate the potential risk factors for such early readmission.Data obtained from 32,457 patients with MRA were analyzed, and of these 7,799 individuals (24.03%) were unplanned readmitted within 30-day follow-up. The mortality rate in the readmitted population was 15.15%. Patients at younger age were at a higher risk of readmission. The morbidities including hypertension (OR=1.117, 95%CI: 1.054-1.184), hyperlipemia (OR=1.075, 95%CI: 1.009-1.146) and diabetes (OR=1.118, 95%CI: 1.053-1.188), gastrointestinal malignancies and peritoneal procedure significantly increased the risk of 30-day readmission in patients with MRA. More than one in five patients with MRA was unplanned readmitted within 30-day follow-up. The above risk factors should be timely intervened and the corresponding medical care should be strengthened in patients with MRA to lessen the unplanned 3 readmission and improve the readmission outcomes.

    Keywords: Malignancy-related ascites, Readmission, Nationwide Readmissions Database, malignancy, Ascites

    Received: 01 Jun 2024; Accepted: 23 Jul 2024.

    Copyright: © 2024 Guan, Tian, Huang, Guo, Zhao, Liu and Yu. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence: Qingbo Guan, Shandong Provincial Hospital, Jinan, China

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