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CASE REPORT article

Front. Oncol.
Sec. Thoracic Oncology
Volume 14 - 2024 | doi: 10.3389/fonc.2024.1408456

Giant ganglioneuroma of the mediastinum: A Case Report

Provisionally accepted
Linfeng Song Linfeng Song 1Jiaren Zhang Jiaren Zhang 1BINLIN TIAN BINLIN TIAN 1Li Yongzhe Li Yongzhe 1Xiaoyu Gu Xiaoyu Gu 1Youlun Zhang Youlun Zhang 2Lin Jiang Lin Jiang 1*
  • 1 Department of Radiology, First People’s Hospital of Zunyi, Zunyi, China
  • 2 Department of Pathology, First People’s Hospital of Zunyi, Zunyi, Guizhou, China

The final, formatted version of the article will be published soon.

    Ganglioneuroma (GN) is a rare benign neurogenic tumour that originates from the sympathetic nerves. It is extremely uncommon to find a lesion originating from the mediastinum that occupies the entire left hemithorax. In this report, we present the case of a 48-year-old female patient with a large mediastinal GN who presented with cough, sputum, and wheezing. Multislice spiral-enhanced CT and magnetic resonance imaging (MRI) revealed a large oval mass in the left thoracic cavity. The surgical operation completely resected the lesion, and the histopathological examination of the resected specimen confirmed the diagnosis of giant ganglion cell neuroma of the mediastinum. Due to the low incidence of GN and the lack of specific imaging manifestations, many radiologists may lack sufficient knowledge of GN and may be prone to misdiagnosis, resulting in delayed treatment.To enhance radiologists' awareness of giant ganglion cell neuroma of mediastinal origin occupying the thoracic cavity, we provided detailed CT/MRI imaging information for this case, along with a brief summary of similar previously reported cases, to highlight the specific clinical and radiological features of this condition.

    Keywords: Ganglioneuroma, Mediastinum, Thoracic Cavity, CT, MRI, case report

    Received: 27 Jun 2024; Accepted: 27 Sep 2024.

    Copyright: © 2024 Song, Zhang, TIAN, Yongzhe, Gu, Zhang and Jiang. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence: Lin Jiang, Department of Radiology, First People’s Hospital of Zunyi, Zunyi, China

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