AUTHOR=Mispelbaum Rebekka , Hattenhauer Tessa , Bauernfeind Franz-Georg , Lau Jan-Frederic , Brossart Peter , Heine Annkristin 

TITLE=Case report: Ipilimumab and nivolumab in metastatic adrenocortical cancer with high tumor mutational burden

JOURNAL=Frontiers in Oncology

VOLUME=Volume 14 - 2024

YEAR=2024

URL=https://www.frontiersin.org/journals/oncology/articles/10.3389/fonc.2024.1406616

DOI=10.3389/fonc.2024.1406616

ISSN=2234-943X

ABSTRACT=-Patient consent for publication: The patient's sister provided after the patient's death her consent for the case report to be published by signing an informed consent form. Conflict of Interest Statement: R.M., T.H. and J.F.L. have no conflicts of interest to declare, F.G.B., P.B., A.H.: advisory boards and speaker activities for BMS, research funding from BMS -Authors' contributions: R.M. and T.H. wrote the manuscript, A.H. critically revised the manuscript, JF L carried out the pathological analyses for the images. All others gave critical input.-Acknowledgment: We thank Jonathan Baden und Gina Fusaro for their support and for providing study-specific information.List of abbreviations: progression free survival (PFS), immune checkpoint inhibitors (CPIs), cytotoxic T-lymphocyte-associated protein 4 (CTLA-4), programmed death-ligand 1 (PD-L1), programmed cell death protein 1 (PD-1), tumor mutational burden (TMB)