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CASE REPORT article
Front. Oncol.
Sec. Thoracic Oncology
Volume 14 - 2024 |
doi: 10.3389/fonc.2024.1403260
This article is part of the Research Topic Pancreatic, Lung, and Stomach Cancer Awareness Month View all 5 articles
Case Report: Pancreatic metastasis from small cell lung cancer appears as primary G2 pancreatic neuroendocrine tumor on combined contrast PET imaging with three probes
Provisionally accepted- 1 Cancer Center, The First Hospital of Jilin University, Changchun, China
- 2 Department of Radiology, First Affiliated Hospital of Jilin University, Changchun, Jilin Province, China
Pancreatic metastases is a rare malignant tumor, when comes to multiple cancers, it may be a challenge to identify the primary lesion of new pancreatic metastases. With the continuous advancement of imaging technology, the PET/CT has been widely used due to its high diagnostic accuracy and non-invasiveness. However, in the present case, the patient had history of limited-small cell lung carcinoma and prostatic cancer, the combined application of three kinds of PET/CT was used to identify the new metastases of pancreatic and bone metastases, which suggested high probability of primary G2 pancreatic neuroendocrine tumor with bone metastases. After the needle biopsy, samples were confirmed by diagnostic pathology as small cell lung cancer metastasizing to the pancreas and bone. The results of our case suggests the irreplaceability of pathology and possibility of misdiagnosis by PET/CT, besides, it also supplements clinical data for second primary cancers after small cell lung cancer.
Keywords: Small Cell Lung Cancer, Pancreatic metastasis, primary pancreatic neuroendocrine carcinoma, PET/CT, differential diagnosis, Multiple primary cancers
Received: 19 Mar 2024; Accepted: 30 Aug 2024.
Copyright: © 2024 Zhang, Cong, Yin, Liu and Xiong. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence:
Xiaofeng Cong, Cancer Center, The First Hospital of Jilin University, Changchun, China
Jiaxin Yin, Cancer Center, The First Hospital of Jilin University, Changchun, China
Ziling Liu, Cancer Center, The First Hospital of Jilin University, Changchun, China
Wenji Xiong, Department of Radiology, First Affiliated Hospital of Jilin University, Changchun, 11003057, Jilin Province, China
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