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BRIEF RESEARCH REPORT article
Front. Oncol.
Sec. Thoracic Oncology
Volume 14 - 2024 |
doi: 10.3389/fonc.2024.1396637
This article is part of the Research Topic Community Series in Reducing Adverse Effects of Cancer Immunotherapy: Volume II View all 10 articles
Relationship between nausea and vomiting and physical activity in patients with lung cancer undergoing first chemotherapy
Provisionally accepted- 1 Shanghai East Hospital, School of Medicine, Tongji University, Shanghai, China
- 2 Department of Obstetrics and Gynecology, School of Medicine, Tongji University, Shanghai, Shanghai Municipality, China
- 3 Department of Oncology, Shanghai East Hospital, School of Medicine, Tongji University, Shanghai, China
- 4 shanghai east hospital, shanghai, China
Objective Nausea and vomiting are the distressing and debilitating side effects of chemotherapy. This study explores the relationship between the degree of nausea and vomiting and physical activity in patients with lung cancer during the first chemotherapy cycle. Design A total of 107 patients with lung cancer who received platinum drugs during chemotherapy in a hospital in Shanghai, China, in 2023 were involved in this study. Data were collected with medical record system and self-reported questionnaires.Questionnaires included the International Physical Activity Questionnaire (IPAQ) and Index of Nausea, Vomiting, and Retching (INVR). IPAQ was used before chemotherapy; INVR was used on the second and sixth day of chemotherapy, followed by the analysis of the correlation between physical activity status and degree of nausea and vomiting during chemotherapy. The influencing factors of nausea and vomiting during chemotherapy in patients with lung cancer were analyzed using logistic regression analysis.More than half of the patients experienced nausea, vomiting or retching related symptoms after chemotherapy, and the proportion of moderate to high physical activity was 50.5%.Univariate analysis showed that the degree of nausea and vomiting was influenced by factors such as age, gender, and history of drinking (P < 0.05). The degree of nausea and vomiting was negatively correlated with physical activity (P < 0.05). The multivariate linear analysis showed that gender, history of drinking, and moderate and high physical activity are contributing factors to nausea and vomiting during chemotherapy (P < 0.05).
Keywords: lung cancer, Nausea, Vomiting, Platinum, physical activity
Received: 06 Mar 2024; Accepted: 03 Jul 2024.
Copyright: © 2024 Bai, Duan, Zhang, lv, li and zhang. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence:
Xia Duan, Department of Obstetrics and Gynecology, School of Medicine, Tongji University, Shanghai, Shanghai Municipality, China
Weiying Zhang, Department of Oncology, Shanghai East Hospital, School of Medicine, Tongji University, Shanghai, China
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