AUTHOR=Ding Lipeng , Zheng Zhangcai , Cao Yueao , Wang Zhenjiang , Zhu Baoyu , Miao Guoying , Yuan Wenzhen 

TITLE=Case report: Cervical brachytherapy technique for locally advanced cervical cancer in a patient with complete bicorporeal uterus

JOURNAL=Frontiers in Oncology

VOLUME=14

YEAR=2024

URL=https://www.frontiersin.org/journals/oncology/articles/10.3389/fonc.2024.1361562

DOI=10.3389/fonc.2024.1361562

ISSN=2234-943X

ABSTRACT=<sec><title>Purpose</title><p>The purpose of this study was to describe an approach to cervical brachytherapy for a patient with a complete bicorporeal uterus and locally advanced cervical cancer (LACC).</p></sec><sec><title>Materials and methods</title><p>The patient was a 53-year-old woman with a complete bicorporeal uterus, diagnosed with stage IIB cervical squamous cell carcinoma due to contact bleeding. The patient underwent concurrent chemoradiotherapy (CCRT), external beam pelvic radiotherapy with 45 Gy/25 fractions, and weekly cisplatin (40 mg/m<sup>2</sup>). Brachytherapy was administered following the completion of external beam radiotherapy.</p></sec><sec><title>Results</title><p>The brachytherapy, which was CT (Computed Tomography)-guided using two CT-compatible tandems and two CT-compatible ovoids, delivered a prescription dose of HRCTV D90 was 6 Gy*5F, which achieved satisfactory dose coverage. The patient’s final HRCTV D90 EQD2<sub>10</sub> was 84.9 Gy, and IRCTV D90 EQD2<sub>10</sub> was 63.5 Gy. Rectum D2cc EQD2<sub>3</sub> was 66.03 Gy, bladder D2cc EQD2<sub>3</sub> was 75.57 Gy, sigmoid D2cc EQD2<sub>3</sub> was 63.93 Gy, and intestine D2cc EQD2<sub>3</sub> was 65.86 Gy. Follow-up at 1 year was CR.</p></sec><sec><title>Conclusions</title><p>For patients with cervical cancer and a complete bicorporeal uterus, using double tandems combined with double ovoids is a feasible treatment method to ensure adequate dose coverage without causing additional damage. This method is also applicable to patients with endometrial cancer.</p></sec>