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CASE REPORT article

Front. Oncol.
Sec. Neuro-Oncology and Neurosurgical Oncology
Volume 14 - 2024 | doi: 10.3389/fonc.2024.1355119

Spindle Cell Sarcoma and Pituitary Adenoma in the Sella Region -A rare Collision Tumor: Case Report and Literature Review

Provisionally accepted
Peng-Fei Ding Peng-Fei Ding Ting Zhu Ting Zhu Yue Cui Yue Cui HUiying Yan HUiying Yan Yun-Feng Wang Yun-Feng Wang Chunhua Hang Chunhua Hang Wei Li Wei Li *
  • Nanjing Drum Tower Hospital, Nanjing, Jiangsu Province, China

The final, formatted version of the article will be published soon.

    Background：Collision tumors are defined as two or more distinctly bordered, mutually invasive tumors in the same anatomical region. Characterized by low incidence and no specificity, they often pose a significant challenge to disease diagnosis. Among them, the sella region's collision tumors are incredibly uncommon.Case description: On June 13, 2023, the Department of Neurosurgery at Drum Tower Hospital, admitted a patient with pituitary adenoma in the sella region complicated with spindle cell sarcoma. After reviewing the literature, no related cases were reported. A patient with complex clinical symptoms and preoperative imaging showing sella region occupancy, considered to have a recurrence of pituitary adenoma. After thorough preoperative evaluation and discussion, a transsphenoidal approach (with the aid of an endoscope) was performed to resection the pituitary lesions. Combined with postoperative pathologic tissue and imaging, the patient was diagnosed with a pituitary adenoma (postoperative recurrence) in the sella region complicated by spindle cell sarcoma. The patient made a fair recovery and was discharged on the 8th postoperative day.This case report aims to elucidate and discuss the diagnosis and screening of rare sella region collision tumors, to reduce the misdiagnosis rate, and then to provide accurate treatment.

    Keywords: Collision Tumor, sella region, Spindle cell sarcoma, pituitary adenoma, case report

    Received: 13 Dec 2023; Accepted: 31 Oct 2024.

    Copyright: © 2024 Ding, Zhu, Cui, Yan, Wang, Hang and Li. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence: Wei Li, Nanjing Drum Tower Hospital, Nanjing, 210008, Jiangsu Province, China

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