AUTHOR=Liu Xiao li , Zhao Jinxin , Di Xue min , Cao Guohui , Zhang Hongtao , Wang Juan TITLE=Case report: Highly response to low-dose brachytherapy in recurrent retroperitoneal leiomyosarcoma with FANCD2 frameshift mutation: a unique case study JOURNAL=Frontiers in Oncology VOLUME=14 YEAR=2024 URL=https://www.frontiersin.org/journals/oncology/articles/10.3389/fonc.2024.1339955 DOI=10.3389/fonc.2024.1339955 ISSN=2234-943X ABSTRACT=

We report a case of recurrent retroperitoneal leiomyosarcoma in a male who achieved a rapid and robust but transient clinical response to low-dose iodine-125 brachytherapy. A FANCD2 frameshift mutation was detected by gene sequencing in the cancerous tissue.