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ORIGINAL RESEARCH article

Front. Oncol.
Sec. Head and Neck Cancer
Volume 14 - 2024 | doi: 10.3389/fonc.2024.1331578

Feasibility Study of Dual-Accelerated Simultaneous Multi-Slice Imaging in Diffusion Tensor Imaging of Glioma

Provisionally accepted
Yakun He Yakun He XiaoYu Chen XiaoYu Chen Siqing Yi Siqing Yi Min Wang Min Wang Jin Ren Jin Ren Peng Zhou Peng Zhou Heping Deng Heping Deng *
  • Sichuan Cancer Hospital, Chengdu, Sichuan Province, China

The final, formatted version of the article will be published soon.

    Objective: To explore the value of dual-accelerated simultaneous multi-slice (SMS) imaging in diffusion tensor imaging (DTI) of glioma.Methods: Thirty-four patients with glioma who underwent magnetic resonance imaging (MRI) in our hospital from January 2022 to March 2023 were randomly selected. The results of dual-accelerated SMS-DTI and conventional DTI were retrospectively analyzed. All patients were scanned using a uMR790 3.0T MRI scanner, and the scanning technicians followed a predefined sequence to ensure consistency in scan parameters. The images were subjectively evaluated using a Likert 5-point scoring system. Objective evaluation was performed by measuring the required values of the images with b-value = 1000 s/mm 2 , primarily measuring the signal intensity in the tumor region and the contralateral normal brain white matter region. The standard deviation values were used to calculate the signal-to-noise ratio (SNR) and contrast-to-noise ratio (CNR) in the same encoding direction as the background noise. The number of generated fiber pathways, fractional anisotropy (FA), and mean diffusivity (MD) were measured and analyzed using post-processing software. The relative FA (rFA) and relative MD (rMD) were calculated.The results of conventional DTI and SMS-accelerated DTI were compared. In terms of subjective evaluation, including overall image quality, tumor edge clarity, and magnetic sensitivity artifacts, both techniques showed no significant differences, indicating comparable diagnostic performance in anatomical visualization. In terms of objective evaluation and quantitative parameter measurement, there were statistically significant differences in SNR and CNR values, with slightly lower values in the dualaccelerated SMS-DTI compared with conventional DTI，a significant reduction in scanning time can be achieved through a slight loss in image quality. The number of fiber pathways and the rFA and rMD values did not show typical differences between the two techniques. The correlation between these measures was highly similar, with no significant differences observed.The application of dual-accelerated simultaneous multi-slice imaging in DTI of glioma is feasible.

    Keywords: Magnetic Resonance Imaging, simultaneous multi-slice, Diffusion Tensor Imaging, Glioma, SNR，CNR

    Received: 01 Nov 2023; Accepted: 27 Aug 2024.

    Copyright: © 2024 He, Chen, Yi, Wang, Ren, Zhou and Deng. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence: Heping Deng, Sichuan Cancer Hospital, Chengdu, 610041, Sichuan Province, China

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