Skip to main content

CASE REPORT article

Front. Oncol.
Sec. Cancer Imaging and Image-directed Interventions
Volume 14 - 2024 | doi: 10.3389/fonc.2024.1324732
This article is part of the Research Topic Precision Medical Imaging for Cancer Diagnosis and Treatment - Vol. II View all 28 articles

Case Report: Extraskeletal Mesenchymal Chondrosarcoma with Rare Metastasis to the Pancreas

Provisionally accepted
Xiuliang Zhu Xiuliang Zhu 1Lu Cheng Lu Cheng 2Fei Dong Fei Dong 1Jinsong Cai Jinsong Cai 1Wei Qian Wei Qian 1Qiao-Ling Ding Qiao-Ling Ding 3*
  • 1 Department of Radiology, Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang Province, China
  • 2 Department of Pathology, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China
  • 3 Department of Radiology, Hangzhou Xixi hospital, Hangzhou, Jiangsu Province, China

The final, formatted version of the article will be published soon.

    Background: Extraskeletal mesenchymal chondrosarcoma (ESMC), an uncommon and highly aggressive form of chondrosarcoma, is characterized by its mesenchymal origin and absence of skeletal involvement. Only few cases of primary ESMC with metastasis to the pancreas have been reported so far. In this study, we present a case of ESMC in the left thigh with a solitary pancreatic metastasis in a 45-year-old woman. Additionally, we provide a thorough overview of ESMC, encompassing its entire clinical progression and radiographic observations. Furthermore, we examine reviewed all instances thirteen cases of pancreatic metastasis, including this present case, analyzing patient attributes, clinical management, and prognosis.Case Presentation: A woman of 45 years old came with a painless mass in her left thigh for one year. X ray, CT and MRI of the left thigh were performed. PET-CT imaging showed a high accumulation in both the left thigh tumor and the pancreatic neck lesion. A diagnosis of extraskeletal chondrosarcoma with pancreatic metastasis was determined based on the radiological examinations.examinations after surgical resection. The patient presented metastasis in lung, right groin and tail of pancreas successively, and mostly received complete surgical excision during a 39-month followup with postoperative chemotherapy.We present a highly uncommon case of ESMC spreading to the pancreas and highlight the importance of recognizing the distinctive imaging features of ESMC for diagnosis and prognosis assessment.

    Keywords: Soft Tissue Neoplasms, Mesenchymal chondrosarcoma, metastasis, Contrast-enhanced computed tomography, Magnetic Resonance Imaging

    Received: 20 Oct 2023; Accepted: 11 Sep 2024.

    Copyright: © 2024 Zhu, Cheng, Dong, Cai, Qian and Ding. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence: Qiao-Ling Ding, Department of Radiology, Hangzhou Xixi hospital, Hangzhou, Jiangsu Province, China

    Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.