AUTHOR=Velasco-Hidalgo Liliana , González-Garay Alejandro , Segura-Pacheco Blanca Angélica , Esparza-Silva Ana Luisa , Cuéllar Mendoza Miguel Enrique , Ochoa-Drucker Cecilia , Campos-Ugalde Sofía , Bernabé-Gaspar Luis Eduardo , Zapata-Tarrés Marta TITLE=Virtual reality as a non-medical tool in the treatment of anxiety, pain, and perception of time in children in the maintenance phase of acute lymphoblastic leukemia treatment JOURNAL=Frontiers in Oncology VOLUME=14 YEAR=2024 URL=https://www.frontiersin.org/journals/oncology/articles/10.3389/fonc.2024.1303421 DOI=10.3389/fonc.2024.1303421 ISSN=2234-943X ABSTRACT=Introduction

Management of pediatric cancer patients involves invasive procedures such as punctures, injections, catheter placements, and chemotherapy which can generate fatigue, nausea, vomiting, anxiety, and pain. Virtual Reality (VR) is a nonpharmacological intervention classified as a cognitive-behavioral method to relieve symptoms.

Methods

We designed a crossover protocol and included 20 patients between 9 and 12 years old; ten were male. All patients had acute lymphoblastic leukemia diagnosis and were treatedwith St. Jude’s XV protocol in the maintenance phase. Pain and anxiety were measured with validated scales in the pediatric population.

Results

Although we used a small group of patients, we found statistical difference in the reduction of anxiety and perception of time.

Discussion

These results open a window to non-pharmacological treatments and show a strategy to improve quality of life in children inside the hospital.