AUTHOR=Zanoni Michele , Borges da Silva Henrique , Adinolfi Elena TITLE=Editorial: Therapy resistance in tumor microenvironment: metabolic reprogramming and purinergic signaling JOURNAL=Frontiers in Oncology VOLUME=13 YEAR=2023 URL=https://www.frontiersin.org/journals/oncology/articles/10.3389/fonc.2023.1297152 DOI=10.3389/fonc.2023.1297152 ISSN=2234-943X