AUTHOR=Zhao Yi , Diao Wei , Li Suping , Yang Mengxi , Cheng Zhuzhong 

TITLE=Case Report: a rare primary gastric choriocarcinoma revealed on 18F-FDG PET/CT

JOURNAL=Frontiers in Oncology

VOLUME=13

YEAR=2023

URL=https://www.frontiersin.org/journals/oncology/articles/10.3389/fonc.2023.1227236

DOI=10.3389/fonc.2023.1227236

ISSN=2234-943X

ABSTRACT=<p>Choriocarcinoma is an exceptionally aggressive trophoblastic cell tumor that that typically originates in gonadal tissues, with rare occurrences outside the gonads, including the mediastinum, retroperitoneum, and intracranial sites. However, it rarely occurs in the stomach. Herein, we presented a case of primary gastric choriocarcinoma in a 27-year-old female patient who found multiple liver masses detected during physical examination, accompanied by remarkably elevated human chorionic gonadotropin levels. The <sup>18</sup>F-FDG PET/CT scan suggested ring-shaped intense uptake masses located in the gastric sinus and liver, and no significance in the pelvic region. Final histopathology indicated primary choriocarcinoma of the stomach. This case illustrates that <sup>18</sup>F-FDG PET/CT is an essential imaging technique for the clinical diagnosis and stage of primary choriocarcinoma.</p>