AUTHOR=Zhao Fangrui , Yang Dashuai , Xu Tangpeng , He Jiahui , Guo Jin , Li Xiangpan 

TITLE=New treatment insights into pancreatic acinar cell carcinoma: case report and literature review

JOURNAL=Frontiers in Oncology

VOLUME=13

YEAR=2023

URL=https://www.frontiersin.org/journals/oncology/articles/10.3389/fonc.2023.1210064

DOI=10.3389/fonc.2023.1210064

ISSN=2234-943X

ABSTRACT=<p>Pancreatic acinar cell carcinoma (PACC) is a rare pancreatic malignancy with unique clinical, molecular, and morphologic features. The long-term survival of patients with PACC is substantially better than that of patients with ductal adenocarcinoma of the pancreas. Surgical resection is considered the first choice for treatment; however, there is no standard treatment option for patients with inoperable disease. The patient with metastatic PACC reported herein survived for more than 5 years with various treatments including chemotherapy, radiotherapy, antiangiogenic therapy and combined immunotherapy.</p>