AUTHOR=Pinto Soniya N. , Chiang Jason , Qaddoumi Ibrahim , Livingston David , Bag Asim TITLE=Pediatric diencephalic tumors: a constellation of entities and management modalities JOURNAL=Frontiers in Oncology VOLUME=13 YEAR=2023 URL=https://www.frontiersin.org/journals/oncology/articles/10.3389/fonc.2023.1180267 DOI=10.3389/fonc.2023.1180267 ISSN=2234-943X ABSTRACT=

The diencephalon is a complex midline structure consisting of the hypothalamus, neurohypophysis, subthalamus, thalamus, epithalamus, and pineal body. Tumors arising from each of these diencephalic components differ significantly in terms of biology and prognosis. The aim of this comprehensive review is to describe the epidemiology, clinical symptoms, imaging, histology, and molecular markers in the context of the 2021 WHO classification of central nervous system neoplasms. We will also discuss the current management of each of these tumors.