AUTHOR=Hong Yejun , Nixon Nancy , Cao Jeffrey Q. , Lee Sangjune Laurence TITLE=Case report: Ultrahypofractionated palliative breast radiotherapy for a fungating invasive mammary carcinoma JOURNAL=Frontiers in Oncology VOLUME=13 YEAR=2023 URL=https://www.frontiersin.org/journals/oncology/articles/10.3389/fonc.2023.1171444 DOI=10.3389/fonc.2023.1171444 ISSN=2234-943X ABSTRACT=

Palliative radiotherapy for symptomatic and intact breast tumors must balance convenience, efficacy, and risk of acute toxicity. This case report presents a patient with metastatic breast cancer and an intact fungating primary tumor. She was treated with an ultrahypofractionated radiation therapy, 26 Gy in 5 consecutive daily fractions, with sequential palliative chemotherapy. This resulted in a minimal toxicity profile and significant reduction of tumor burden and symptoms.