AUTHOR=Si Mao-Yan , Rao Ding-Yu , Xia Yao , Sang Cheng-Peng , Mao Kai-Yun , Liu Xiang-Jin , Zhang Zu-Xiong , Tang Zhi-Xian 

TITLE=Role of exosomal noncoding RNA in esophageal carcinoma

JOURNAL=Frontiers in Oncology

VOLUME=Volume 13 - 2023

YEAR=2023

URL=https://www.frontiersin.org/journals/oncology/articles/10.3389/fonc.2023.1126890

DOI=10.3389/fonc.2023.1126890

ISSN=2234-943X

ABSTRACT=Esophageal cancer is one of the most prevalent malignant tumors with high mortality. Understanding its pathogenesis and identifying early diagnostic biomarkers can significantly improve the prognosis of esophageal cancer patients. Exosomes are small double-membrane vesicles found in various body fluids containing various components (DNA, RNA, and proteins) that mediate intercellular material exchange and signal communication. There is growing evidence that exosomes and their components are involved in cancer growth, metastasis, and angiogenesis and can also be used as diagnostic and prognostic markers. This article reviews the recent progress in exosomes' role in esophageal cancer, including research progress, diagnostic value, proliferation, migration, invasion, and drug resistance.