AUTHOR=Abdullah Norlia , Rizuana Iqbal Hussain , Goh Janice Hui Ling , Lee Qi Zheng , Md Isa Nurismah , Md Pauzi Suria Hayati 

TITLE=Bilateral metachronous breast malignancies: Malignant phylloides and invasive breast carcinoma—a case report

JOURNAL=Frontiers in Oncology

VOLUME=13

YEAR=2023

URL=https://www.frontiersin.org/journals/oncology/articles/10.3389/fonc.2023.1034556

DOI=10.3389/fonc.2023.1034556

ISSN=2234-943X

ABSTRACT=<p>A 57-year-old Malay nullipara initially presented with a right breast lump that was increasing in size but defaulted follow-up. Two years later, she developed a contralateral breast lump. She only returned to the hospital when the right breast lump had become painful, 4 years from its onset. The biopsy of the right breast lump was a phylloides tumor and that of the left breast lump was a carcinoma. She had bilateral palpable axillary lymph nodes. She underwent bilateral mastectomy and axillary dissection. The pathology report confirmed the right breast lesion to be a malignant phylloides and the left breast lesion to be a carcinoma (pT3N2). She declined adjuvant treatment. A year after the surgical operation of the metachronous lesions, she had a right chest wall recurrence with widespread pulmonary metastases. She was given palliative chemotherapy but succumbed several months later.</p>