AUTHOR=Xie Yunkai , Kong Weimin , Zhao Xiaoling , Zhang He , Luo Dan , Chen Shuning 

TITLE=Immune checkpoint inhibitors in cervical cancer: Current status and research progress

JOURNAL=Frontiers in Oncology

VOLUME=12

YEAR=2022

URL=https://www.frontiersin.org/journals/oncology/articles/10.3389/fonc.2022.984896

DOI=10.3389/fonc.2022.984896

ISSN=2234-943X

ABSTRACT=<p>Cervical cancer is the second most common gynecological malignant tumor endangering the health of women worldwide. Despite advances in the therapeutic strategies available to treat cervical cancer, the long-term prognosis of patients with recurrent and metastatic cervical cancer remains unsatisfactory. In recent years, immune checkpoint inhibitors (ICIs) have shown encouraging efficacy in the treatment of cervical cancer. ICIs have been approved for use in both first- and second-line cervical cancer therapies. This review summarizes the current knowledge of ICIs and the application of ICIs in clinical trials for the treatment of cervical cancer.</p>