AUTHOR=Li Feiyu , Jiang Yong , Jiang Liyong , Li Qingbin , Yan Xiangyu , Huang Songhan , Chen Ji , Yuan Shuai , Fu Yingda , Liu Jun 

TITLE=Effect of lymph node resection on prognosis of resectable intrahepatic cholangiocarcinoma: A systematic review and meta-analysis

JOURNAL=Frontiers in Oncology

VOLUME=Volume 12 - 2022

YEAR=2022

URL=https://www.frontiersin.org/journals/oncology/articles/10.3389/fonc.2022.957792

DOI=10.3389/fonc.2022.957792

ISSN=2234-943X

ABSTRACT=Background:The purpose of this meta-analysis was to evaluate the efficact of lymph node dissection in patients with intrahepatic cholangiocarcinoma.
Methods:The literatures from January 2009 to December 2021 were searched to determine the comparative study of lymph node dissection and non-lymph node dissection in ICC patients.
Results:17 studies were included in the analysis. There were no significant differences in 1,3,5-year overall survival(OR 0.80 p=0.10; OR 0.93 p=0.71; OR 0.80 p=0.21) and 1,3,5-year disease-free survival(OR 0.89 p=0.73; OR 0.92 p=0.81; OR 0.85 p=0.62).
Conclusions:Lymph node dissection does not seem to have a positive effect on the overall survival and disease-free survival.