AUTHOR=Siracusano Salvatore , Zaka Agustina , Bassi Pierfrancesco , Gontero Paolo , Mearini Ettore , Imbimbo Ciro , Simonato Alchiede , Dal Moro Fabrizio , Giannarini Gianluca , Valotto Claudio , Montorsi Francesco , Colombo Renzo , Porpiglia Francesco , Bartoletti Riccardo , Vella Marco , Minervini Andrea , Porcaro Antonio Benito , Romantini Federico , Vicentini Carlo , Talamini Renato , Ficarra Vincenzo , Lonardi Cristina TITLE=Quality-of-Life Outcomes in Female Patients With Ileal Conduit or Orthotopic Neobladder Urinary Diversion: 6-Month Results of a Multicenter Prospective Study JOURNAL=Frontiers in Oncology VOLUME=12 YEAR=2022 URL=https://www.frontiersin.org/journals/oncology/articles/10.3389/fonc.2022.855546 DOI=10.3389/fonc.2022.855546 ISSN=2234-943X ABSTRACT=

Radical cystectomy (RC) often affects patients’ life as this surgery is a traumatic and invasive event for the patients, with drawbacks on their daily, social, working, and sex life. Such changes in the quality of life (QoL) of patients are commonly studied through retrospective clinical evaluations and rarely with longitudinal studies. To date, studies focusing on functional outcomes, sexual function, and health-related QoL for female patients are lacking. We evaluated 37 patients using EORTC QLQ-C30 (QLQ-30) and Short-Form 36 (SF-36) questionnaires, before and after surgery, at 3 and 6 months of follow-up. The mean values for the emotional functioning in QLQ-C30 as well as the mental health in SF-36 were significantly higher in the ONB group compared to the IC group at 3 months of follow-up. These differences were not significant at 6 months of follow-up. At 6 months of follow-up, the ONB group showed a higher mean score in the physical and role functioning than the IC group. Although there was a statistically significant age difference at baseline of the two groups, none of the results are correlated with age, as demonstrated by Spearman’s analysis. The ONB seems to represent the most advantageous solution compared to the IC in terms of QOL at the 6-month follow-up.