AUTHOR=Galavis Paulina E. , Abeloos Camille Hardy , Cheng Pine C. , Hitchen Christine , McCarthy Allison , Purswani Juhi M. , Shah Bhartesh , Taneja Sameer , Gerber Naamit K. 

TITLE=Accelerated partial breast irradiation in early stage breast cancer

JOURNAL=Frontiers in Oncology

VOLUME=12

YEAR=2022

URL=https://www.frontiersin.org/journals/oncology/articles/10.3389/fonc.2022.1049704

DOI=10.3389/fonc.2022.1049704

ISSN=2234-943X

ABSTRACT=<p>Accelerated partial breast irradiation (APBI) is increasingly used to treat select patients with early stage breast cancer. However, radiation technique, dose and fractionation as well as eligibility criteria differ between studies. This has led to controversy surrounding appropriate patients for APBI and an assessment of the toxicity and cosmetic outcomes of APBI as compared to whole breast irradiation (WBI). This paper reviews existing data for APBI, APBI delivery at our institution, and ongoing research to better define patient selection, treatment delivery, dosimetric considerations and toxicity outcomes.</p>