AUTHOR=Chen Ping , Song Haolin , Xu Wei , Guo Jin , Wang Jianfei , Zhou Juhong , Kang Xiang , Jin Chaolei , Cai Yubo , Feng Zixuan , Gao Hainv , Lu Fengmin , Li Lanjuan 

TITLE=Validation of the GALAD model and establishment of a new model for HCC detection in Chinese patients

JOURNAL=Frontiers in Oncology

VOLUME=Volume 12 - 2022

YEAR=2022

URL=https://www.frontiersin.org/journals/oncology/articles/10.3389/fonc.2022.1037742

DOI=10.3389/fonc.2022.1037742

ISSN=2234-943X

ABSTRACT=GALAD model is a model used to estimate the possibility of HCC in patients with chronic liver disease.However, whether this model can be used for Chinese patients remains to be determined. Our study was conducted to verify the performance of GALAD model in a Chinese population and construct a new model that is more appropriately for Chinese samples.There are total 445 patients enrolled in our study, and the GAADPB model was established by logistic regression.The new GAADPB model was powerful and stable, with better performance than the GALAD and other models，and it also was promising in the area of HCC prognosis prediction. Further study on the real-world HCC patients in China are needed.