AUTHOR=Cui Manman , Zhai Duchang , Liu Yan , Zhou Xiuzhi , Wang Tingting , Wang Lihuan , Cai Wu , Fan Guohua , Ju Shenghong 

TITLE=Case report: Primary mediastinal Ewing’s sarcoma presenting with chest tightness

JOURNAL=Frontiers in Oncology

VOLUME=12

YEAR=2023

URL=https://www.frontiersin.org/journals/oncology/articles/10.3389/fonc.2022.1020339

DOI=10.3389/fonc.2022.1020339

ISSN=2234-943X

ABSTRACT=<p>Ewing’s sarcoma is a part of a rare group of malignant neoplasms, whose pathological morphological features are small round cells. Extraskeletal Ewing’s sarcoma is a more uncommon primary tumor. Herein, we report the case of a 66-year-old man who complained of chest tightness. Subsequent chest CT scans revealed an irregular and uneven density mass on the right side of the anterior mediastinum with invasion of the superior vena cava, pericardium and right lung. The patient’s clinical symptoms were improved after performing excision of the mediastinal lesions under cardiopulmonary bypass. Based on histological and immunohistochemical findings, the tumor was diagnosed as extraskeletal Ewing’s sarcoma.</p>