AUTHOR=Li Xiaobing , Yin Meipan , Xie Pengfei , Liu Ying , Li Xiangnan , Qi Yu , Ma Yaozhen , Li Chunxia , Wu Gang 

TITLE=Self-Expandable Metallic Stent Implantation Combined With Bronchial Artery Infusion Chemoembolization in the Treatment of Lung Cancer With Complete Atelectasis

JOURNAL=Frontiers in Oncology

VOLUME=Volume 11 - 2021

YEAR=2022

URL=https://www.frontiersin.org/journals/oncology/articles/10.3389/fonc.2021.733510

DOI=10.3389/fonc.2021.733510

ISSN=2234-943X

ABSTRACT=Background: Atelectasis is a common complication of lung cancer, and there are few reports about the treatment methods. This study retrospectively analyzed the safety and effectiveness of endotracheal metal stent implantation combined with arterial infusion chemoembolization in the treatment of non-small cell lung cancer with complete atelectasis.
Methods: The clinical data of patients with non-small cell lung cancer and complete atelectasis treated by self-expandable metallic stent implantation combined with arterial infusion chemotherapy were retrospectively analyzed. The clinical efficacy was evaluated and postoperative adverse reactions were observed. Progression-free survival and overall survival were analyzed by Kaplan–Meier method. In all, 42 endotracheal metallic stents were implanted in 42 patients under fluoroscopy: four straight tubular stents, five L-shaped stents, 31 large Y-shaped stents, and two small Y-shaped stents.
Results: After 5–7 days of stent implantation, CT showed that 24 patients (57.1%) had complete lung recruitment, and 13 (31.0%) had partial lung recruitment. The technical success rate was 100%, and the clinical success rate was 88.1% (37/42). After 5–7 days  of stent implantation, bronchial artery infusion chemoembolization was performed in all patients, wherin27 patients received arterial infusion chemoembolization once, 11 patients received it twice, and four patients received it thrice. The median progression-free survival and overall survival were 6 months (95% CI: 2.04–9.66) and 10 months (95% CI: 7.22–12.79), respectively.
Conclusion: Self-expandable metallic stent implantation combined with arterial infusion chemoembolization may be an effective and safe strategy in the treatment of lung cancer with atelectasis,  and can be attempted clinically.